Zaid Mammo

Biography

Dr. Zaid Mammo is a subspecialist in the medical and surgical management of retinal diseases. He completed his ophthalmology residency at the University of British Columbia. He completed subspecialty fellowship training in medical and surgical retina at the prestigious Edward Harkness Eye Institute at Columbia University, New York under the tutelage of Professor Stanley Chang. Following this year, he underwent further training in retinal surgery at Sydney Eye Hospital, Australia’s largest and busiest center for retinal surgery training and research.

Dr. Mammo ’s practice focuses on vitreoretinal surgery and medical retinal disorders, including: diabetic retinopathy, age-related macular degeneration, retinal vascular occlusions, retinal tears, retinal detachment, macular hole, epiretinal membrane as well as other diseases of the retina and vitreous.

In addition to caring for patients, Dr. Mammo has been actively involved in retinal research with a special emphasis on emerging treatments of retinal disorders and advanced non-invasive imaging modalities of the retina and optic nerve. He helped in establishing the Advanced Retinal Imaging and Analysis Laboratory (ARIAL) at the Eye Care Centre of Vancouver General Hospital. His research work has been supported by grants by the Retina Foundation of Canada, Canadian Glaucoma Research Society and Canadian Cancer Society.

As a clinical assistant professor, Dr. Mammo is involved in the training of medical students, resident and fellows at the University of British Columbia. In addition, he currently serves as the Retina Rotation Lead for the Post-graduate Ophthalmology Residency Program at the University of British Columbia. He is also an active surgical instructor in the world-renowned UBC surgical retina fellowship program

Research

Dr. Mammo’s research interests centre around exploring the role of advanced retinal imaging in the early diagnosis, follow-up and management of retinal diseases. As a resident, he was involved in establishing the Advanced Retinal Imaging and Analysis Laboratory (ARIAL), a collaborative effort that combines clinical faculty from UBC with biomedical engineering expertise from Simon Fraser University (SFU).

This collaborative effort has facilitated the introduction of cutting-edge non-invasive retinal imaging technology including Optical Coherence Tomography-Angiography (OCT-A) and OCT-Adaptive Optics (OCT-AO) into the province of British Columbia. These modalities would allow clinicians to evaluate the microvascular structures of the human retina including the microvasculature as well as the retinal photoreceptors, the light-sensing cells in the eye. Since the inception of ARIAL in 2016, our group has published over twenty OCT-related publications in high-impact journals including Investigative Ophthalmology and Visual Sciences, British Journal of Ophthalmology and the American Journal of Ophthalmology.

Currently, Dr. Mammo and his research team are in the process of evaluating the role of wide-field hand-held OCT systems as well as Polarization-sensitive OCT (PS-OCT) in adult and pediatric retinal diseases. Another area of interest is studying retinal vascular dysregulation using OCT-A in a variety of ocular diseases. These research efforts are generously supported by research grants from the Canadian Glaucoma Research Society and Canadian Cancer Society.

Dr. Mammo is always keen to collaborate with individuals from all backgrounds, you can reach him through: dr.mammo@eyecarecentre.org

Publications

1: Bhalla M, Mammo Z. Ectopia Lentis as a Cause for Acute Vision Loss in the

Emergency Department. J Emerg Med. 2021 Jan 20:S0736-4679(20)31346-9. doi:

10.1016/j.jemermed.2020.11.044.

2: Simunovic MP, Hess K, Avery N, Mammo Z. Threshold versus intensity functions

in two-colour automated perimetry. Ophthalmic Physiol Opt. 2021

Jan;41(1):157-164. doi: 10.1111/opo.12743.

3: Heisler M, Bhalla M, Lo J, Mammo Z, Lee S, Ju MJ, Beg MF, Sarunic MV. Semi-

supervised deep learning based 3D analysis of the peripapillary region. Biomed

Opt Express. 2020 Jun 19;11(7):3843-3856. doi: 10.1364/BOE.392648.

4: Heisler M, Karst S, Lo J, Mammo Z, Yu T, Warner S, Maberley D, Beg MF,

Navajas EV, Sarunic MV. Ensemble Deep Learning for Diabetic Retinopathy

Detection Using Optical Coherence Tomography Angiography. Transl Vis Sci

Technol. 2020 Apr 13;9(2):20. doi: 10.1167/tvst.9.2.20.

5: Gong D, Chang JS, Barbany M, Corcostegui BF, Kağan Değirmenci MF, Ishikawa H,

Mammo Z, Ozmert E, Rossi T, Chang S. Comparison of United States and

International Ophthalmic Drug Pricing. Ophthalmology. 2019

Oct;126(10):1358-1365. doi: 10.1016/j.ophtha.2019.04.018.

6: Pakdel AR, Mammo Z, Lee S, Forooghian F. Normal Variation of Photoreceptor

Outer Segment Volume With Age, Gender, Refractive Error, and Vitreomacular

Adhesion. Ophthalmic Surg Lasers Imaging Retina. 2018 Jul 1;49(7):523-527. doi:

10.3928/23258160-20180628-09.

7: Yu PK, Mammo Z, Balaratnasingam C, Yu DY. Quantitative Study of the Macular

Microvasculature in Human Donor Eyes. Invest Ophthalmol Vis Sci. 2018 Jan

1;59(1):108-116. doi: 10.1167/iovs.17-22542.

8: Pakdel A, Mammo Z, Hollands H, Forooghian F. Regression of Subretinal

Lymphoma After Diagnostic Vitrectomy. JAMA Ophthalmol. 2017 May

1;135(5):503-505. doi: 10.1001/jamaophthalmol.2017.0464.

9: Heisler M, Lee S, Mammo Z, Jian Y, Ju M, Merkur A, Navajas E, Balaratnasingam

C, Beg MF, Sarunic MV. Strip-based registration of serially acquired optical

coherence tomography angiography. J Biomed Opt. 2017 Mar 1;22(3):36007. doi:

10.1117/1.JBO.22.3.036007.

10: Mammo Z, Guo M, Maberley D, Matsubara J, Etminan M. Reply. Am J Ophthalmol.

2017 Apr;176:255-256. doi: 10.1016/j.ajo.2017.01.009.

11: Mammo Z, Heisler M, Balaratnasingam C, Lee S, Yu DY, Mackenzie P, Schendel

S, Merkur A, Kirker A, Albiani D, Navajas E, Beg MF, Morgan W, Sarunic MV.

Quantitative Optical Coherence Tomography Angiography of Radial Peripapillary

Capillaries in Glaucoma, Glaucoma Suspect, and Normal Eyes. Am J Ophthalmol.

2016 Oct;170:41-49. doi: 10.1016/j.ajo.2016.07.015.

12: Prentašic P, Heisler M, Mammo Z, Lee S, Merkur A, Navajas E, Beg MF, Šarunic

M, Loncaric S. Segmentation of the foveal microvasculature using deep learning

networks. J Biomed Opt. 2016 Jul 1;21(7):75008. doi: 10.1117/1.JBO.21.7.075008.

13: Mammo Z, Forooghian F. INCIDENCE OF ACUTE EXUDATIVE MACULOPATHY AFTER REDUCED-FLUENCE PHOTODYNAMIC THERAPY. Retin Cases Brief Rep. 2017 Summer;11(3):217-220. doi: 10.1097/ICB.0000000000000356.

14: Fahim AT, Simunovic MP, Mammo Z, Mitry D, Pakzad-Vaezi K, Bradley P, Mahroo

1. Comparison of ophthalmic training in 6 English-speaking countries. Can J

Ophthalmol. 2016 Jun;51(3):212-8. doi: 10.1016/j.jcjo.2016.04.018.

15: Mammo Z, Guo M, Maberley D, Matsubara J, Etminan M. Oral Bisphosphonates and Risk of Wet Age-Related Macular Degeneration. Am J Ophthalmol. 2016

Aug;168:62-67. doi: 10.1016/j.ajo.2016.04.022.

16: Mammo Z, Almeida DR, Cunningham MA, Chin EK, Mahajan VB. ACANTHAMOEBA ENDOPHTHALMITIS AFTER RECURRENT KERATITIS AND NODULAR SCLERITIS. Retin Cases

Brief Rep. 2017 Spring;11(2):180-182. doi: 10.1097/ICB.0000000000000323.

17: Pakzad-Vaezi K, Mehta H, Mammo Z, Tufail A. Vascular endothelial growth

factor inhibitor use and treatment approach for choroidal neovascularization

secondary to pathologic myopia. Expert Opin Biol Ther. 2016 Jul;16(7):873-81.

doi: 10.1517/14712598.2016.1167868.

18: Almeida DR, Mammo Z, Chin EK, Mahajan VB. SURGICAL EMBOLECTOMY FOR FOVEA-THREATENING ACUTE RETINAL ARTERY OCCLUSION. Retin Cases Brief Rep. 2016 Fall;10(4):331-3. doi: 10.1097/ICB.0000000000000257.

19: Yu PK, Balaratnasingam C, Xu J, Morgan WH, Mammo Z, Han S, Mackenzie P,

Merkur A, Kirker A, Albiani D, Sarunic MV, Yu DY. Label-Free Density

Measurements of Radial Peripapillary Capillaries in the Human Retina. PLoS One.

2015 Aug 7;10(8):e0135151. doi: 10.1371/journal.pone.0135151.

20: Mammo Z, Balaratnasingam C, Yu P, Xu J, Heisler M, Mackenzie P, Merkur A,

Kirker A, Albiani D, Freund KB, Sarunic MV, Yu DY. Quantitative Noninvasive

Angiography of the Fovea Centralis Using Speckle Variance Optical Coherence

Tomography. Invest Ophthalmol Vis Sci. 2015 Aug;56(9):5074-86. doi:

10.1167/iovs.15-16773.

21: Tan PE, Balaratnasingam C, Xu J, Mammo Z, Han SX, Mackenzie P, Kirker AW,

Albiani D, Merkur AB, Sarunic MV, Yu DY. Quantitative Comparison of Retinal

Capillary Images Derived By Speckle Variance Optical Coherence Tomography With

Histology. Invest Ophthalmol Vis Sci. 2015 Jun;56(6):3989-96. doi:

10.1167/iovs.14-15879.

22: Chan G, Balaratnasingam C, Xu J, Mammo Z, Han S, Mackenzie P, Merkur A,

Kirker A, Albiani D, Sarunic MV, Yu DY. In vivo optical imaging of human retinal

capillary networks using speckle variance optical coherence tomography with

quantitative clinico-histological correlation. Microvasc Res. 2015 Jul;100:32-9.

doi: 10.1016/j.mvr.2015.04.006.

23: Xu J, Han S, Balaratnasingam C, Mammo Z, Wong KS, Lee S, Cua M, Young M,

Kirker A, Albiani D, Forooghian F, Mackenzie P, Merkur A, Yu DY, Sarunic MV.

Retinal angiography with real-time speckle variance optical coherence

tomography. Br J Ophthalmol. 2015 Oct;99(10):1315-9. doi:

10.1136/bjophthalmol-2014-306010.

24: Leung VC, Jin YP, Hatch W, Mammo Z, Trope GE, Buys YM, Macrae WG. The

relationship between sociodemographic factors and persistence with topical

glaucoma medications. J Glaucoma. 2015 Jan;24(1):69-76. doi:

10.1097/IJG.0000000000000081.

25: Mammo ZN, Yousif F, Lam WC. Educational outcomes of The University of

Toronto Visiting Professor Rounds Series. Can J Ophthalmol. 2014

Feb;49(1):96-101. doi: 10.1016/j.jcjo.2013.09.019.

26: Mammo ZN, Flanagan JG, James DF, Trope GE. Generic versus brand-name North American topical glaucoma drops. Can J Ophthalmol. 2012 Feb;47(1):55-61. doi:

10.1016/j.jcjo.2011.12.004..

27: Anraku A, Jin YP, Butty Z, Jinapriya D, Alasbali T, Mammo Z, Flanagan JG,

Trope GE. The Toronto epidemiology glaucoma survey: a pilot study. Can J

Ophthalmol. 2011 Aug;46(4):352-7. doi: 10.1016/j.jcjo.2011.06.013.

28: Razik R, Mammo Z, Gill HS, Lam WC. Academic screencasting: internet-based

dissemination of ophthalmology grand rounds. Can J Ophthalmol. 2011

Feb;46(1):72-6. doi: 10.3129/i10-093.

Professional Memberships:

• American Academy of Ophthalmology
• Canadian Ophthalmological Society
• Vitreous-Buckle Society
• American Society of Retina Specialists
• American Retina Forum
• Association for Research in Vision and Ophthalmology
• British Columbia Society for Eye Physicians and Surgeons

To be Filled.